FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmacology and medicine. An agent represents peptide of general formula A-Pro-Tyr-B-X (I) where Pro can represent DPro, A is chosen from Ala, Gly, IIe, Leu, Met, Phe, Ser, Thr, Trp, Tyr, Val; B is chosen from Ala, Arg, Cly, IIe, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr, Val; X-OH; -OCH3; -NH2; -Cly-Pro, and is described as perspective for producing new drugs able to reduce positive and negative symptomatology of schizophrenia and other psychoses.
EFFECT: offered is the agent exhibiting antipsychotic activity.
4 dwg, 9 tbl, 15 ex
| Title | Year | Author | Number |
|---|---|---|---|
| FAMILY OF PEPTIDES POSSESSING ANALGESIC ACTIVITY | 2005 |
|
RU2286169C1 |
| PEPTIDES WITH ANTICOAGULANT, FIBRINOLYTIC, ANTI-PLATELET AND ANTI-THROMBOSIS ACTIVITY | 2005 |
|
RU2286166C1 |
| HEXAPEPTIDE ELICITING MEMORY STIMULATING ACTIVITY | 1998 |
|
RU2131743C1 |
| PEPTIDE POSSESSING ANTI-COAGULANT, FIBRIN-DEPOLYMERIZATION, ANTI-THROMBOSIS AND FIBRINOLYTIC ACTIVITIES | 2005 |
|
RU2288736C1 |
| PEPTIDE POSSESSING ANTICOAGULANT, FIBRIN-DEPOLYMERIZING, ANTI-THROMBOSIS AND FIBRINOLYTIC ACTIVITIES | 2005 |
|
RU2289423C1 |
| HEPTAPEPTIDE ELICITING ANALGETIC ACTIVITY COMBINING WITH THERMOREGULATORY AND/OR VASOMOTOR ACTIVITY AND/OR WITH EFFECT ON BEHAVIOR RESPONSE OF TESTING ORGANISM AND METHOD OF ALTERNATION OF PHYSIOLOGICAL ACTIVITY OF DERMORPHINE | 1997 |
|
RU2134121C1 |
| PEPTIDE AND A METHOD OF ITS SYNTHESIS | 1994 |
|
RU2067000C1 |
| METHOD OF PRODUCING RECOMBINANT PEPTIDE AND OBTAINED PEPTIDE | 2012 |
|
RU2507212C2 |
| METHOD OF PREPARING POLYPEPTIDES | 0 |
|
SU904518A3 |
| METHOD FOR PRODUCING PEPTIDES | 0 |
|
SU1316565A3 |
