FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a mixture of sodium laquinimod crystal particles wherein 10% or more of total volume of sodium laquinimod particles are sized more than 40 micron. Also, the invention refers to the mixture of sodium laquinimod crystal particles of tap density at least 0.6 g/ml, to a pharmaceutical composition, to a composition, to a method of sodium laquinimod recrystallisation, as well as to a method for preparing the pharmaceutical composition.
EFFECT: preparation of the new biologically active compounds used for treatment of disease caused by autoimmune or pathological inflammation.
39 cl, 17 ex, 5 tbl, 3 dwg
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Authors
Dates
2011-04-10—Published
2006-10-18—Filed