SODIUM LAQUINIMOD CRYSTALS AND METHOD FOR MAKING THEREOF Russian patent published in 2011 - IPC C07D215/22 A61K31/4704 A61P37/02 A61P29/00 

Abstract RU 2415841 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a mixture of sodium laquinimod crystal particles wherein 10% or more of total volume of sodium laquinimod particles are sized more than 40 micron. Also, the invention refers to the mixture of sodium laquinimod crystal particles of tap density at least 0.6 g/ml, to a pharmaceutical composition, to a composition, to a method of sodium laquinimod recrystallisation, as well as to a method for preparing the pharmaceutical composition.

EFFECT: preparation of the new biologically active compounds used for treatment of disease caused by autoimmune or pathological inflammation.

39 cl, 17 ex, 5 tbl, 3 dwg

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RU 2 415 841 C2

Authors

Frenkel Anton

Gurevich Ehduard

Lakser Avital

Dates

2011-04-10Published

2006-10-18Filed