COMBINED ANTITUBERCULOUS PHARMACEUTICAL COMPOSITION Russian patent published in 2011 - IPC A61K31/606 A61K31/4409 A61K9/20 A61P31/06 

Abstract RU 2417087 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical field, and concerns a combined antituberculous pharmaceutical composition in a solid dosage form including a therapeutically effective amount of an active principle which is represented by a combination of sodium para-aminosalicylate and isoniazid, and pharmaceutically acceptable auxiliary substances, in the following proportions, wt % of total composition: sodium para-aminosalicylate - 36.8-90.41; isoniazid-1.08-3.38; auxiliary substances - the rest.

EFFECT: invention provides longer high blood serum concentration of active preparations, as well as prevents development of mycobacterium drug resistance to isoniazid.

4 cl, 8 tbl, 3 ex

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RU 2 417 087 C2

Authors

Punija Vikram Singkh

Gushchin Aleksandr Sergeevich

Fedorov Dmitrij Viktorovich

Malygin Aleksej Vladimirovich

Zorkal'Tseva Elena Jul'Evna

Dates

2011-04-27Published

2008-12-03Filed