FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical field, and concerns a combined antituberculous pharmaceutical composition in a solid dosage form including a therapeutically effective amount of an active principle which is represented by a combination of sodium para-aminosalicylate and isoniazid, and pharmaceutically acceptable auxiliary substances, in the following proportions, wt % of total composition: sodium para-aminosalicylate - 36.8-90.41; isoniazid-1.08-3.38; auxiliary substances - the rest.
EFFECT: invention provides longer high blood serum concentration of active preparations, as well as prevents development of mycobacterium drug resistance to isoniazid.
4 cl, 8 tbl, 3 ex
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Authors
Dates
2011-04-27—Published
2008-12-03—Filed