PHARMACEUTICAL COMPOSITION FOR PARENTERAL APPLICATION OF 2-ETHYL-6-METHYL-3-HYDROXYPYRIDINE SUCCINATE AND METHOD OF OBTAINING SAID COMPOSITION Russian patent published in 2011 - IPC A61K31/44 A61K9/08 A61K33/04 

Abstract RU 2419432 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to chemical-pharmaceutical industry and medicine and deals with composition for parenteral introduction, which contains (wt %): 2-ethyl-6-methyl-3-hydroxypyridine succinate as active component - 4.0-6.0; stabiliser - sodium metabisulfite - 0.015-0.045 and water as solvent - to 100. Claimed invention also relates to method of obtaining said composition. Composition is characterised by stability during three years, low toxicity, comparable with 2-ethyl-6-methyl-3-hydroxypyridine succinate solution without stabilisers, makes it possible to realise therapeutic action of active substance without undesirable side pharmacologic activity of auxiliary substances.

EFFECT: invention can be used in medicine as medication for treatment and prevention of various diseases and pathological states of human organism.

3 cl, 6 ex, 2 tbl

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RU 2 419 432 C1

Authors

Zabozlaev Aleksandr Aleksandrovich

Kovalev Vasilij Petrovich

Dates

2011-05-27Published

2010-04-07Filed