METHOD OF PREDICTING EFFICIENCY OF PLANNED STANDARD THERAPY OF ACUTE NEPHRITIS Russian patent published in 2011 - IPC A61B5/00 

Abstract RU 2421126 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, nephrology and can be used in treatment of acute nephritis. Biochemical indices of patient's blood - concentration of interferon-γ (IFN-γ, (pg/ml)), immunoglobulin E (IgE, (unit/ml)) and interleukin-4 (IL-4, (pg/ml)) is determined. Obtained results are substituted in formula of discriminant function (DF): DF=21.85×IFN-γ+3.10×lgE+29.91×IL-4-5435.36 and development of inadequate response to standard therapy is predicted in case if DF value is negative.

EFFECT: method makes it possible to predict favourable or unfavourable development of pathologic process in response to standard treatment with 90% probability, to intensify treatment in case of necessity, reducing probability of early exacerbations of chronic nephritis.

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RU 2 421 126 C1

Authors

Fedicheva Natal'Ja Aleksandrovna

Khanferjan Roman Avakovich

Bagdasar'Jan Arshak Sarkisovich

Agaeva Zoja Abuevna

Gorbov Leonid Valentinovich

Shakhraj Jurij Ivanovich

Dates

2011-06-20Published

2010-01-25Filed