METHOD FOR PREDICTING THE CLINICAL COURSE OF POSTINFECTIOUS GLOMERULONEPHRITIS Russian patent published in 2019 - IPC G01N33/53 

Abstract RU 2691402 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely nephrology, and aims at predicting the clinical course of post-infection glomerulonephritis. Method includes immunosorbent analysis of biosubstrate on content of cytokines – interleukin-1β (IL-1β) and receptor antagonist IL-1β (RAIL-1β) in disease onset. Biosubstrate is urine, wherein the prognostic index is determined relative to IL-1β/RAIL-1β. If the prognostic index is less than 0.000094 in the postinfection glomerulonephritis patients, the possibility of the chronic course of the disease is predicted, and with IL-1β/RAIL-1β index valuehigher than 0.019, but less than 0.056, predicting acute postinfection glomerulonephritis.

EFFECT: using the given method enables obtaining an early prognosis of the clinical course of the postinfectious glomerulonephritis.

1 cl, 3 ex, 7 tbl

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RU 2 691 402 C1

Authors

Kudryashov Sergej Igorevich

Karzakova Luiza Mikhajlovna

Avtonomova Olga Ilinichna

Leonteva Ekaterina Viktorovna

Dates

2019-06-13Published

2018-10-15Filed