COMPOSITION WITH MODIFIED RELEASE, CONTAINING1-[(3-HYDROXYADAMANT-1-YLAMINO)ACETYL]PYRROLIDIN-2(S)-CARBONITRYL Russian patent published in 2011 - IPC A61K31/40 A61K9/22 A61K9/24 

Abstract RU 2423124 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to pharmaceutical composition for obtaining tablets, which includes in one standard form, for instance, in one tablet, the following ingredients: (a) active ingredient, such as (S)-1-[(3-hydroxy-1-adamantyl)amino]acetyl-2-cyano-pyrrolidin (vildagliptin), or its pharmaceutically acceptable salt, (b) hydroxypropylmethylcellulose, whose apparent viscosity in 1% solution constitutes from 80000 cP to 120000 cP (nominal value 100000 cP), (c) microcrystalline cellulose and (d) magnesium stearate.

EFFECT: composition possesses high stability and efficiency.

35 cl, 42 tbl, 26 dwg

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RU 2 423 124 C2

Authors

Koval'Ski Dzhejms

Lakshman Dzhej Partiban

Adzhuddin Abu T. M.

Dzhoshi Jatindra

Dates

2011-07-10Published

2006-06-08Filed