FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to pharmaceutical composition for obtaining tablets, which includes in one standard form, for instance, in one tablet, the following ingredients: (a) active ingredient, such as (S)-1-[(3-hydroxy-1-adamantyl)amino]acetyl-2-cyano-pyrrolidin (vildagliptin), or its pharmaceutically acceptable salt, (b) hydroxypropylmethylcellulose, whose apparent viscosity in 1% solution constitutes from 80000 cP to 120000 cP (nominal value 100000 cP), (c) microcrystalline cellulose and (d) magnesium stearate.
EFFECT: composition possesses high stability and efficiency.
35 cl, 42 tbl, 26 dwg
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Authors
Dates
2011-07-10—Published
2006-06-08—Filed