METHOD OF PREVENTING POST-OPERATION NAUSEA AND VOMITING IN CHILDREN IN OTOLARYNGOLOGICAL SURGERY Russian patent published in 2011 - IPC A61K31/4468 A61P1/08 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, and can be used for prevention of post-operation nausea and vomiting in children in otolayngologic (ENT) surgery. Premedication is performed. Dexametazone is introduced in dose 0.2 mg/kg i/v, 8 mg maximum. Propofol is introduced in dose 2-3 mg/kg i/v, fentanyl 4-5 mcg/kg i/v with anesthesia induction. Anesthesia is performed with nitrous oxide - oxygen mixture N₂O+O₂ with ratio 2:1. Propofol 2.5-3.5 mg/kg/hour i/v, fentanyl 3-4 mcg/kg/hour in micro-jet manner in basis-anesthesia. When operation is over, metoclopromide is introduced in dose 0.2 mg/kg i/v not more than 10 mg. After extubation oxygenation with oxygen through facial mask in dose 3-4 l/min is carried out for 3-5 minutes.

EFFECT: method makes it possible to prevent syndrome of post-operation nausea and vomiting in children in ENT surgery.

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