FIELD: medicine.
SUBSTANCE: invention relates to field of medicine, namely to narcology. In order to predict recurrences of opium addiction in patient monthly carried out is incubation of lymphocytes in vitro in two samples: in presence of morphine in dose 10-6 M and in its absence - with further hystochemical staining for 5'-nucleotidase and semi-quantitative evaluation of said staining efficiency in points. Ratio of average points of staining for 5'-nucleotidase in lymphocytes, incubated with morphine and in its absence is calculated by division of first index by second. If said ratio decreases by more than 30% in comparison with the norm, appropriate preventive treatment is administered to patient.
EFFECT: method makes it possible to predict recurrences of opium addiction after withdrawal of patients from abstinence syndrome, due to detection of biological marker, anticipating clinical manifestations of recurrence.
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Authors
Dates
2011-09-10—Published
2010-04-20—Filed