SUGAR COATINGS AND METHODS OF THEIR APPLICATION Russian patent published in 2011 - IPC A61K9/20 A61K9/36 A61K47/26 A61K47/30 A61K47/38 A61K31/567 A61K31/57 A61P5/30 A61J3/06 

FIELD: medicine, pharmaceutics.

SUBSTANCE: application relates to composition for application of sugar coatings by method of spraying directly on core material with obtaining of hard drug form. According to invention, composition includes water and hard component, representing mixture of sugar, binding agent, hydroxyalkylcellulose, water-soluble polymer, therapeutic agent, second polymer, which is water-soluble or dispersible in water and plasticiser. Invention also relates to hard drug form, in particular, tablet for peroral introduction, which has described above coating, and as therapeutic agent, in core material contains conjugated estrogens. Invention also relates to method of said sugar coating application, which includes core obtaining, application of coating composition on core material and in case of necessity application of colour and glossy coatings.

EFFECT: invention ensures obtaining coatings which demonstrate good mechanical strength and elasticity when applied on substrate, thus reducing probability of cracks development; in addition, application of water-soluble system in coating composition makes it possible to minimise application of organic solvents in process of film coating application.

110 cl, 1 dwg, 11 ex