FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, and describes a pharmaceutical composition for neurodegenerative diseases of hydrogenated pyrido(4,3-b)indole, a method for preparing and based drug. The pharmaceutical composition consists of hydrogenated pyrido(4,3-b)indole (Rs) and a polymeric component (Rp) selected from: blood serum albumin, sodium alginate, amylopectin, hydroxyethyl starch, dextrane, gelatin, sodium caseinate, carboxymethyl cellulose, carrageenan, starch, phosphorylated starch, lactalbumin, methylcellulose, ovalbumin, pectin, polyvinylpyrrolidone, sodium polygalacturonate, lactic-co-glycolic acid, cyclodextrin, (2-hydroxypropyl)cyclodextrin or their mixtures, and Rs and Rp are associated and found in the composition in the following proportions (weight fractions): Rs 10-60, Rp 40-90. The method for preparing the declared pharmaceutical composition consists in the fact that the components Rs and Rp are dissolved in a common solvent, kept at temperature -40 to +50°C for 0.5 to 8 h and dried by the known method.
EFFECT: group of inventions solves a problem of preparing the drugs which would exhibit high therapeutic activity in small doses and would not cause side effects.
3 cl, 3 ex, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| REMEDY FOR IMPROVEMENT OF COGNITIVE FUNCTIONS AND MEMORY BASED ON HYDRATED PYRIDO (4,3-b) INDOLES (VERSIONS), PHARMACOLOGICAL REMEDY BASED THEREON AND METHOD OF APPLICATION THEREOF | 2006 |
|
RU2334514C1 |
| AGENT FOR TREATMENT OF ACUTE AND CHRONIC DISTURBANCES OF CEREBRAL CIRCULATION, INCLUDING STROKE ON BASIS OF HYDROGENATED PYRIDO (4,3-b)INDOLES (VERSIONS), PHARMACOLOGICAL AGENT ON ITS BASIS AND METHOD OF ITS APPLICATION | 2006 |
|
RU2340342C2 |
| ANTIDEPRESSIVE AND ANTIHYPOXIC AGENT OF 2,8-DIMETHYL-5-[2- (6-METHYL-PYRIDYL-3)-ETHYL]-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-b]INDOLE SALTS AND BASED PHARMACEUTICAL COMPOSITION | 2009 |
|
RU2425046C1 |
| NEW APPROACH TO TREATMENT OF ALZHEIMER'S DISEASE | 1995 |
|
RU2106864C1 |
| GEROPROTECTING AGENT BASED ON HYDROGENATED PYRIDO[4,3-b]INDOLES (VARIANTS), PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD FOR ITS USING | 2003 |
|
RU2283108C2 |
| AGENT POSSESSING ANXIOLYTHIC ACTION, ON BASIS OF HYDROGENATED PYRIDO (4,3-b) INDOLES (VERSIONS), PHARMACOLOGICAL AGENT ON ITS BASIS AND WAY OF ITS APPLICATION | 2007 |
|
RU2338533C1 |
| METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA WITH USING NEUROLEPTIC COMBINED THERAPY | 2007 |
|
RU2508096C2 |
| METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA WITH USING ATYPICAL NEUROLEPTIC COMBINED THERAPY | 2007 |
|
RU2508106C2 |
| AGENT FOR NEUTRALISING TOXIC ACTION OF TUMOUR NECROSIS FACTOR ON BASIS OF HYDRATED PYRIDO(4,3-b)INDOLES, PHARMACOLOGICAL AGENT ON ITS BASIS AND METHOD OF TREATING AUTOIMMUNE DISEASE ON BASIS OF NEUTRALISING TOXIC ACTION OF TUMOUR NECROSIS FACTOR | 2012 |
|
RU2477131C1 |
| AGENT FOR TREATMENT OF SCHIZOPHRENIA ON BASIS OF HYDROGENATED PYDIDO (4,3-b) INDOLES (VERSIONS), PHARMACOLOGICAL AGENT ON ITS BASIS AND METHOD OF ITS APPLICATION | 2006 |
|
RU2338537C2 |
