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2 106 864

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IPC

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Application

95118252/14, 1995-10-23

(22)

Actual filing date

1995-10-23

(45)

Published

1998-03-20

(72)

Inventor

Zefirov Nikolaj SerafimovichAfanas'Ev Andrej ZakharovichAfanas'Eva Svetlana Vasil'EvnaBachurin Sergej OlegovichTkachenko Sergej Evgen'EvichGrigor'Ev Vladimir ViktorovichJurovskaja Marina AbramovnaChetverikov Valerij PavlovichBukatina Elizaveta Evgen'EvnaGrigor'Eva Irina Vladimirovna

(73)

Holder

NEW APPROACH TO TREATMENT OF ALZHEIMER'S DISEASE Russian patent published in 1998 - IPC

Abstract RU 2106864 C1

FIELD: medicine; treatment of neurodegenerative diseases, in particular Alzheimer's disease. SUBSTANCE: it is recommended to use hydrogenated pyrido (4,3-6) indoles of general formula 1 , in which R1, R2, R3 are as defined in specification. These compounds are NMDA antagonists and are useful in treating neurodegenerative diseases, in particular, Alzheimer's disease. Invention reports results of examination of patients affected with Alzheimer's disease before and after administration of DIMEBON, one of compounds covered by general formula 1. EFFECT: improved results in treatment of difficult-to-treat Alzheimer's disease. 36 tbl

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RU 2 106 864 C1

Authors

Zefirov Nikolaj Serafimovich

Afanas'Ev Andrej Zakharovich

Afanas'Eva Svetlana Vasil'Evna

Bachurin Sergej Olegovich

Tkachenko Sergej Evgen'Evich

Grigor'Ev Vladimir Viktorovich

Jurovskaja Marina Abramovna

Chetverikov Valerij Pavlovich

Bukatina Elizaveta Evgen'Evna

Grigor'Eva Irina Vladimirovna

Dates

1998-03-20—Published

1995-10-23—Filed