METHOD OF TREATING OPTIC NERVE BY TRANSPLANTATION OF AUTOLOGIC STEM CELLS Russian patent published in 2011 - IPC A61F9/00 A61K35/28 A61P27/00 A61P25/02 A61M25/00 

Abstract RU 2428956 C2

FIELD: medicine.

SUBSTANCE: method includes delivery of biological material into area of optic nerve by injection parabulbarly, as well as by means of two microdrainages through the incision of sclera into sub-Tenon's and suprachoroidal spaces of eye. As biological material used is autologic cell material in form of suspension of bone marrow mononuclears, which contains patient's stem cells on carrier solution in concentration from 100000 to 1000000 cells per ml of suspension. Introduction is performed in portions every 1-2 hours up to 10 times per day for each separate way of introduction. Parabulbarly 1 ml per injection is introduced. Through microdrainages in sub-Tenon's space introduced are 1-4 ml per injection, into suprachoroidal space - 0.1-0.3 ml per injection.

EFFECT: reduction of blindness and visual impairedness with restoration of structure and functioning of optic nerve due to induction of organotypic tissue regeneration, including vascular net of optic nerve, its disc and peripapillar choroidea.

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RU 2 428 956 C2

Authors

Romashchenko Aleksandr Dmitrievich

Kovalev Aleksej Vjacheslavovich

Dates

2011-09-20Published

2009-07-13Filed