FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and pharmaceutical industry, and concerns a pharmaceutical oral formulation for nicotine or its derivative delivery to a subject by means of oral mucosa absorption, containing nicotine where the above-stated oral formulation is buffered with at least tromethanole.
EFFECT: what is presented is the method of oral nicotine delivery for reduction of craving to smoke or use tobacco, and also the methods for preparing the oral formulation, applying the oral formulation for nicotine uptake in the subject's mouth and applying nicotine for making the oral formulation for treating tobacco or nicotine dependence.
57 cl, 10 ex
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Authors
Dates
2011-12-20—Published
2007-04-18—Filed