FIELD: medicine, pharmaceutics.
SUBSTANCE: coated pharmaceutical product for nicotine delivery into an individual in any form contains at least one core, nicotine in any form and/or a nicotine-imitating agent, at least one coating layer, and optionally one or more additions wherein at least said coating layer contains a buffer agent containing at least one amino acid. Amino acid is specified in a group consisting of asparagine, glutamic acid, glutamine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, valine, cysteic acid, N-glycylglycine and ornithine. There are also provided a method for nicotine delivery in any form, a method for reduction of craving to smoke or use tobacco, as well as a method for preparing said coated product and applying it for ensuring fast oral nicotine absorption.
EFFECT: invention provides fast oral nicotine absorption; pharmaceutical product under the invention is characterised by the satisfactory organoleptic properties.
49 cl, 3 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COATED PHARMACEUTICAL PRODUCT FOR ORAL NICOTINE DELIVERY CONTAINING TROMETAMOL AS BUFFERING AGENT | 2007 |
|
RU2448707C2 |
| NICOTINE COMPOSITION FOR PERORAL APPLICATION, WHICH CONTAINS AMINO-ACID BUFFER | 2008 |
|
RU2465904C2 |
| PHARMACEUTICAL PRODUCT FOR INTRAORAL NICOTINE ADMINISTRATION CONTAINING TROMETAMOL AS BUFFER AGENT | 2007 |
|
RU2436566C2 |
| NICOTINE-CONTAINING CHEW WITH COVER, METHOD FOR ITS PREPARING AND USING | 2002 |
|
RU2291688C2 |
| MULTICOMPONENT ORAL DOSAGE FORM WITH ORGANOLEPTIC PROPERTIES | 2010 |
|
RU2490010C2 |
| NICOTINE-CONTAINING PHARMACEUTICAL COMPOSITION AND ITS USING | 2002 |
|
RU2282447C2 |
| TABLETTED CHEWING GUMS | 2009 |
|
RU2501551C2 |
| SOLID NICOTINE-CONTAINING DOSAGE FORM WITH REDUCED UNPLEASANT ORGANOLEPTIC IMPACT | 2013 |
|
RU2623018C2 |
| SOLID ORAL NICOTINE COMPOSITION | 2018 |
|
RU2786451C2 |
| DISINTEGRATING ORAL FILMS | 2007 |
|
RU2436565C2 |
