FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing 4-(dimethylamino)-2-butinyl alkanoates, which are of interest in synthesis of physiologically active substances. The method involves reaction of propargyl alkanoates with N,N,N1,N1-tetramethyl methane diamine in the presence of a Sm(NO3)2·6H2O catalyst at temperature 50-100°C, preferably 80°C, and atmospheric pressure for 5-7 hours. Output of 4-(dimethylamino)-2-butinyl alkanoates is equal to 56-96%.
EFFECT: high output of end product.
1cl, 9 ex
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