METHOD OF POSTOPERATIVE THERAPY OF NON-MUSCLE INVASIVE BLADDER CANCER Russian patent published in 2012 - IPC A61K33/00 A61K31/407 A61K31/704 A61P35/00 

Abstract RU 2443423 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly oncology, and can be applied in treating non-muscle invasive bladder cancer. The method involves adjuvant intra-bladder therapy with chemopreparations pre-dissolved in Tisol, aqueous solution. The tumpours with a low risk of relapse and progression require single instillations immediately following the operation of doxorubicine 50 mg or mitomycin 40 mg pre-dissolved in 40% Tisol, aqueous solution 50 ml with the length of exposition 1 h. In the tumours with a medium risk of relapse and progression, the postoperative instillations are added with intra-bladder chemotherapy with doxorubicine 50 mg or mitomycin 40 mg pre-dissolved in Tisol, aqueous solution with the length of exposition 1 h once every 6 weeks.

EFFECT: use of the invention provides higher clinical effectiveness and decreases a degree of side effects due to the adjuvant intra-bladder therapy according to a degree of postoperative risk of relapse and progression of the tumour.

3 tbl, 1 dwg, 5 ex

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Authors

Berzin Sergej Aleksandrovich

Zamjatin Aleksandr Viktorovich

Shamanskij Vjacheslav Bronislavovich

Dates

2012-02-27Published

2009-02-24Filed