FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry, and concerns a liquid 6-decaprenyl-2,3-dimethoxy-5-methyl-1,4-benzoquinone composition which is characterised by high bioavailability and prolonged shelf life. The composition contains an active substance - 6-decaprenyl-2,3-dimethoxy-5-methyl-1,4-benzoquinone, a nonionic surfactant, an antioxidant, a preservative agent, a fat-soluble emulsion stabiliser, water-soluble cellulose derivatives, water-soluble emulsion and water stabiliser. Also, there is offered a method for preparing the composition which consists in the fact that certain amounts of the nonionic surfactant and the antioxidant are mixed, heated to 40-120°C; the required amounts of the fat-soluble emulsion stabiliser and 6-decaprenyl-2,3-dimethoxy-5-methyl-1,4-benzoquinone are dissolved in the prepared solution; the prepared mixture is cooled to 30-60°C and in through mixing added to the mixed solution of the cellulose derivatives, the water-soluble emulsion stabiliser and the preservative agent pre-heated to 30-60°C.
EFFECT: enabled effective method for preparing the composition.
8 cl, 4 ex, 1 tbl
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Authors
Dates
2012-03-20—Published
2010-06-02—Filed