6-DECAPRENYL-2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE COMPOSITION AND METHOD FOR PREPARING IT Russian patent published in 2012 - IPC A61K31/122 A61K9/107 A61P39/06 A61P43/00 

Abstract RU 2445079 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to chemical-pharmaceutical industry, and concerns a liquid 6-decaprenyl-2,3-dimethoxy-5-methyl-1,4-benzoquinone composition which is characterised by high bioavailability and prolonged shelf life. The composition contains an active substance - 6-decaprenyl-2,3-dimethoxy-5-methyl-1,4-benzoquinone, a nonionic surfactant, an antioxidant, a preservative agent, a fat-soluble emulsion stabiliser, water-soluble cellulose derivatives, water-soluble emulsion and water stabiliser. Also, there is offered a method for preparing the composition which consists in the fact that certain amounts of the nonionic surfactant and the antioxidant are mixed, heated to 40-120°C; the required amounts of the fat-soluble emulsion stabiliser and 6-decaprenyl-2,3-dimethoxy-5-methyl-1,4-benzoquinone are dissolved in the prepared solution; the prepared mixture is cooled to 30-60°C and in through mixing added to the mixed solution of the cellulose derivatives, the water-soluble emulsion stabiliser and the preservative agent pre-heated to 30-60°C.

EFFECT: enabled effective method for preparing the composition.

8 cl, 4 ex, 1 tbl

Similar patents RU2445079C2

Title Year Author Number
6-DECAPRENYL-2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE-BASE STABLE AQUEOUS-OILY COMPOSITION AND METHOD FOR ITS PREPARING 2005
  • Shabatin Vladimir Petrovich
  • Pereverzev Mikhail Olegovich
RU2290176C1
COMPOSITION BASED ON 6-DECAPREENYL-2,3-DIMETHOXY-5-METHYL-1,4-BENZOCHINON AND METHOD TO OBTAIN IT 2008
  • Gajdukov Mikhail Ivanovich
  • Enileev Rustam Khalilovich
  • Shabatin Vladimir Petrovich
RU2405543C2
COMPOSITION ON BASIS OF 6-DEKAPRENIL-2,3-DIMETOXY-5-METHYL-1,4-BENZOQUINONE FOR INJECTION INTRODUCTION IN ORGANISM AND WAY OF ITS OBTAINING 2007
  • Shabatin Vladimir Petrovich
  • Arsen'Ev Pavel Sergeevich
RU2359665C2
COMPOSITION WITH 6-DECAPRNYL-2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE FOR PARENTERAL INTRODUCTION AND METHOD OF ITS OBTAINING 2009
  • Pozharitskaja Ol'Ga Nikolaevna
  • Karlina Marina Valer'Evna
  • Shikov Aleksandr Nikolaevich
  • Makarova Marina Nikolaevna
  • Makarov Valerij Gennad'Evich
RU2433820C2
LIPOSOMAL AGENT BASED ON UBIQUINOL AND PREPARATION METHOD THEREOF 2015
  • Demchenko Dmitrij Valentinovich
  • Pozharitskaja Olga Nikolaevna
  • Shikov Aleksandr Nikolaevich
  • Makarov Valerij Gennadevich
  • Makarova Marina Nikolaevna
RU2605616C1
UBIQUINOL COMPOSITION FOR PARENTERAL ADMINISTRATION AND METHOD FOR ITS PRODUCTION 2016
  • Karlina Marina Valerevna
  • Dadali Yurij Vladimirovich
  • Pozharitskaya Olga Nikolaevna
  • Shikov Aleksandr Nikolaevich
  • Makarova Marina Nikolaevna
  • Makarov Valerij Gennadevich
  • Fomichev Yurij Sergeevich
  • Medvedev Oleg Stefanovich
  • Gorodetskaya Evgeniya Aronovna
  • Kalenikova Elena Igorevna
RU2635993C1
COLLOID-RESISTANT MICRO-EMULSION OF WATER-SOLUBLE BIOLOGICALLY ACTIVE SUBSTANCES AND INDUSTRIAL METHOD OF ITS PRODUCTION 2015
  • Sarvalov Makhammad Sarvalovich
  • Kudryashov Nikita Viktorovich
RU2661597C2
METHOD FOR PREPARING BETA-CAROTENE-CONTAINING EMULSION 2001
  • Kapustina V.I.
  • Karpun E.V.
  • Krasnova Z.M.
  • Puchkov E.I.
  • Rozanov S.A.
  • Serpukhovitin I.P.
  • Filina S.N.
  • Chumakov S.I.
RU2221455C2
COLLOID-RESISTANT MICROEMULSION OF WATER-INSOLUBLE BIOLOGICALLY ACTIVE SUBSTANCES AND INDUSTRIAL METHOD OF ITS PRODUCTION (VARIANTS) 2015
  • Sarvalov Makhammad Sarvalovich
  • Kudryashov Nikita Viktorovich
RU2657099C2
AGENT ELICITING ANTIOXIDANT AND ANTIVIRAL ACTIVITIES 2004
  • Kiselev O.I.
  • Maljakshin A.V.
RU2244546C1

RU 2 445 079 C2

Authors

Enileev Rustam Khalilovich

Shabatin Vladimir Petrovich

Dates

2012-03-20Published

2010-06-02Filed