TABLETTED ANTIVIRAL AGENT AND METHOD FOR PREPARING IT Russian patent published in 2012 - IPC A61K31/4162 A61K31/53 A61K47/36 A61K47/02 A61K9/36 A61P31/12 

Abstract RU 2446802 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to pharmaceutics, specifically to a tabletted antiviral agent. The agent contains, wt %: as an active substance - 2-methyl-6-nitro-1,2,4-triazolo[5,1-c]-1,2,4-triazin-7-one sodium salt, dehydrate (60.0-90.0), as an excipient - potato starch and/or lactose (1.0-20.0), as an aerating agent - low-substituted hydroxypropyl cellulose and/or microcrystalline cellulose (0.5-20.0), as antifriction substances - talc (0.2-2.5) and aerosil (0.2-3.0), as a greasing ingredient - magnesium stearate (0.2-3.0), as an agent forming a protective coating - hypromellose (1.0-10.0). The declared agent exhibits virus-inhibiting activity with respect to avian influenza virus, Rift Valley fever viruses, parainfluenza virus, Aujeszky's disease virus, western equine sleeping sickness virus, Venezuelan sleeping sickness virus, respiratory syncytial virus. What is also presented is a method for preparing said tabletted agent.

EFFECT: group of inventions provides the extended range of antiviral preparations due to preparing the tabletted agent having manifested virus-inhibiting action and improved organoleptic properties.

10 cl, 2 dwg, 6 tbl, 4 ex

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RU 2 446 802 C2

Authors

Petrov Aleksandr Jur'Evich

Sorokin Pavel Vladimirovich

Shablokova Anna Sergeevna

Dates

2012-04-10Published

2010-07-16Filed