FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to pharmaceutics, specifically to a tabletted antiviral agent. The agent contains, wt %: as an active substance - 2-methyl-6-nitro-1,2,4-triazolo[5,1-c]-1,2,4-triazin-7-one sodium salt, dehydrate (60.0-90.0), as an excipient - potato starch and/or lactose (1.0-20.0), as an aerating agent - low-substituted hydroxypropyl cellulose and/or microcrystalline cellulose (0.5-20.0), as antifriction substances - talc (0.2-2.5) and aerosil (0.2-3.0), as a greasing ingredient - magnesium stearate (0.2-3.0), as an agent forming a protective coating - hypromellose (1.0-10.0). The declared agent exhibits virus-inhibiting activity with respect to avian influenza virus, Rift Valley fever viruses, parainfluenza virus, Aujeszky's disease virus, western equine sleeping sickness virus, Venezuelan sleeping sickness virus, respiratory syncytial virus. What is also presented is a method for preparing said tabletted agent.
EFFECT: group of inventions provides the extended range of antiviral preparations due to preparing the tabletted agent having manifested virus-inhibiting action and improved organoleptic properties.
10 cl, 2 dwg, 6 tbl, 4 ex
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Authors
Dates
2012-04-10—Published
2010-07-16—Filed