2-METHYLTHIO-6-NITRO-1,2,4-TRIAZOLO[5,1-C]-1,2,4-TRIAZINE-7(4H)-ONE SODIUM SALT DIHYDRATE POSSESSING ANTIVIRAL ACTIVITY Russian patent published in 2007 - IPC C07D487/04 A61K31/53 

Abstract RU 2294936 C1

FIELD: organic chemistry, medicine, virology.

SUBSTANCE: invention relates to biologically active compounds and concerns the development of a novel substance - 2-methylthio-6-nitro-1,2,4-triazolo[5,1-c]-1,2,4-triazine-7-(4H)-one sodium salt dihydrate of the formula: . This compound is designated for treatment and prophylaxis of diseases caused by viruses that are pathogenic form humans and animals. Proposed compound protects against infections caused by Rift Valley fever virus. Also, it shows activity against viruses of WEE(West Equine Encephalomyelitis), parainfluenza, respiratory-syncytium, Aujeszky's disease virus, avian infectious laryngotracheitis virus, avian influenza virus - totally against above 10 RNA- and DNA-containing viruses. The proposed compound is active in curative schedule of its using that is especially valuable.

EFFECT: valuable medicinal properties of compound.

1 cl, 6 tbl, 2 dwg, 7 ex

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RU 2 294 936 C1

Authors

Chupakhin Oleg Nikolaevich

Rusinov Vladimir Leonidovich

Ulomskij Evgenij Nartsissovich

Charushin Valerij Nikolaevich

Petrov Aleksandr Jur'Evich

Kiselev Oleg Ivanovich

Dates

2007-03-10Published

2005-06-29Filed