STABILISED PHARMACEUTICAL FORMULATION WITH ANTIMYCOTIC ACTION Russian patent published in 2012 - IPC A61K31/135 A61P17/02 

Abstract RU 2450807 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, more specifically a pharmaceutical formulation in the form of a gel for the local application showing antimycotic activity and containing an effective amount of terbinafine hydrochloride as an active substance and target additives. The formulation contains the target additives as follows: propylene glycol, UV-filter Benzophenone-3 (Escalol 567), cyclomethicone (DC 345), organosilicone elastomer (DC 9045), acrylate emulsion (Salcare SC 80), organosilicone emulsifier PEG-12 Dimethicone (DC 5329), antioxidant (Tinogard NOA), keratolytic urea, preserving agent (Sharomix MCI), trometamol, and purified water.

EFFECT: invention provides manifested antimycotic action, intensified penetration in derma, contains protective SPF factor which reliably protects an inflamed skin area against negative ultra-violet radiation.

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RU 2 450 807 C1

Authors

Omel'Janchuk Pavel Anatol'Evich

Sergeev Aleksandr Aleksandrovich

Dates

2012-05-20Published

2011-05-11Filed