STABILISED PHARMACEUTICAL GEL WITH ANALGESIC AND ANTI-INFLAMMATORY ACTION Russian patent published in 2012 - IPC A61K31/192 A61K47/02 A61K47/08 A61K47/10 A61K47/18 A61K47/22 A61K47/34 A61K9/00 A61P29/00 

Abstract RU 2450811 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, more specifically to a pharmaceutical gel of ketoprofen with analgesic and anti-inflammatory action. The presented gel contains ketoprofen (1.0-6.0 wt %) and target additives: ethanol - 10.0-20.0 wt %, propyleneglycol - 10.0-20.0 wt %, UV filter Escalol 567 - 1.0-40.0 wt %, cyclomethicone DC 345 - 5.0-20.0 wt %, organosilicone emulsifier DC 5329 - 1.0-4.0 wt %, acrylate emulsion of copolymer Salcare SC80 - 1.0-3.5 wt %, trometamol - 1.0-2.5 wt %, fragrance - 0.2-0.4 wt %, preservative SHAROMIX MCI - 0.1-0.5 wt %, purified water - to 100.0 wt %.

EFFECT: due to said composition of target additives, the invention provides stabilisation of photosensitive ketoprofen and its improved penetration in derma, ethanol reduction in the gel, improved gel protection against microorganisms.

1 tbl, 3 ex

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RU 2 450 811 C1

Authors

Omel'Janchuk Pavel Anatol'Evich

Sergeev Aleksandr Aleksandrovich

Dates

2012-05-20Published

2011-04-25Filed