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2 458 987

(13)

(51)

IPC

C12N15/00(2006-01-01)

(21) (22)

Application

2011126031/10, 2011-06-27

(24)

Start date

2011-06-27

(22)

Actual filing date

2011-06-27

(45)

Published

2012-08-20

(72)

Inventor

Svistunov Andrej AlekseevichLutsenko Sergej ViktorovichFel'Dman Natalija BorisovnaSolov'Ev Andrej Ivanovich

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Pervyj Moskovskij Gosudarstvennyj Meditsinskij Universitet Imeni I.M. Sechenova Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii Vpo Pervyj Mgmu Im. I.M. Sechenova Minzdravsotsrazvitija Rossii)

METHOD FOR PRODUCING RECOMBINANT FRAGMENT OF HUMAN PLASMINOGEN POSSESSING ANTIANGIOGENIC ACTION Russian patent published in 2012 - IPC C12N15/00

Abstract RU 2458987 C1

FIELD: medicine.

SUBSTANCE: what is offered is a method for producing a recombinant polypeptide representing a fragment of human plasminogen with 82 on 341 amino acids, in cells of the host producer E.coli. The invention may be used in the medical industry for carrying out the antiangiogenic therapy.

EFFECT: method provides the high yield of an end product.

4 cl, 3 dwg, 5 ex

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RU 2 458 987 C1

Authors

Svistunov Andrej Alekseevich

Lutsenko Sergej Viktorovich

Fel'Dman Natalija Borisovna

Solov'Ev Andrej Ivanovich

Dates

2012-08-20—Published

2011-06-27—Filed