DRUG POSSESSING ACTOPROTECTIVE, ANTIHYPOXIC, NEUROPROTECTIVE, ANTIAMNESTIC AND THERMOPROTECTIVE ACTIVITY Russian patent published in 2012 - IPC A61K31/4412 A61K31/198 A61P25/00 A61P25/28 A61P9/10 A61P43/00 

FIELD: medicine.

SUBSTANCE: what is offered is application of 2-ethyl-6-methyl-3-oxypiridinium L-asparaginate as a drug possessing actoprotective, antihypoxic, neuroprotectivem antiamnestic and thermoprotective activity. It is shown that actoprotective activity of this chemical compound 1 mg/kg exceeds that of the nearest analogue of the declared drug - Mexidol 5 and 10 mg/kg. Thermoprotective activity of this substance 5 mg/kg twice exceeds that of the nearest analogue of the declared drug - Mexidol 50 and 100 mg/kg. Antihypoxic, neuroprotective and antiamnestic activities of the declared drug in animals of various models exceed and/or are highly competitive with the nearest analogue Mexidol and the other reference preparations.

EFFECT: drug is used for the purpose of higher usual and extreme physical performance, as well as for treating acute and chronic disturbed cerebral circulation, including ischemic stroke and other conditions and diseases accompanied by depression of cognitive functions and neurodegeneration, including in ageing.

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