FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to creation of a medicament having pancreatic and hepatoprotective activity, in particular for the treatment of acute pancreatitis and acute hepatitis. Known 2-ethyl-6-methyl-3-oxypyridinium compound L-asparaginate (6-methyl-2-ethylpyridine-3-ol salt of (2S)-2-aminobutanedioic acid) is used as the agent with pancreas and hepatoprotective activity. Also described is a parenteral dosage form based on 2-ethyl-6-methyl-3-oxypyridinium L-asparaginate, formulated as a solution for injection/infusion.
EFFECT: in animals (by lethality and data from biochemical and morphological studies), said compound and dosage form on its basis are superior to closest analogue of the claimed mexidol (in a much larger dose) and other comparators.
2 cl, 7 tbl, 3 ex
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