STABLE PHARMACEUTICAL COMPOSITION CONTAINING WATER-SOLUBLE VINFLUNINE SALT Russian patent published in 2012 - IPC A61K31/475 A61K9/20 A61K9/48 A61P35/00 

Abstract RU 2462248 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents a stable pharmaceutical composition for treating cancer containing a water-soluble salt of vinflunine ditartrate and at least one diluent, one binding substance, one aerating agent and one lubricating agent wherein the composition is presented in a solid form for oral application wherein: the content of the water-soluble salt of vinflunine ditartrate makes 5 to 80 wt %, the content of the diluent makes 20 to 80 wt % of total weight of the composition, the content of the binding substance makes 1 to 10 wt % of total weight of the composition, the content of the lubricating agent makes 0.5 to 10 wt % of total weight of the composition, the content of the aerating agent makes 1 to 10 wt % of total weight of the composition.

EFFECT: invention provides storage stability at 5°C for 24 months in a sealed package.

19 cl, 8 ex

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RU 2 462 248 C2

Authors

Pejjar Bruno

Avan Zhan-Lui

Bugare Zhoehl'

Dates

2012-09-27Published

2008-07-09Filed