COMPOSITION FOR INTEGRATED TREATMENT OF PATIENTS WITH PRIMARY OPEN-ANGLE GLAUCOMA AND OCULAR SURFACE DISEASES Russian patent published in 2012 - IPC A61K31/683 A61K31/726 A61P27/06 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine, in particular to ophthalmology. A composition for treating patients with primary open-angle glaucoma on the basis of phospholipids, sulphated glycosaminoglycans in physiologic saline represents a liposomal emulsion formed by phospholipids in the form of liposomes of average particle size 0.05-0.22 mcm and sulphated glycosaminoglycans, and additionally contains a hypotensive preparation with phospholipids presented by phosphatidyl choline and/or cardiolipin, and sulphated glycosaminoglycans presented by keratan sulphate sodium salt and chondroitin sulphate sodium salt with the ingredients taken in the following proportions, wt %: Phospholipid 0.001-2.0; Sulphated glycosaminoglycans 0.0001-0.1; The hypotensive preparation 0.0025-0.02; Physiologic saline - the rest with sulphated glycosaminoglycans and the hypotensive preparation found both inside the liposomes, and outside the liposomes, in physiologic saline.

EFFECT: invention provides a prolonged hypotensive effect, prevents lachrymal production, reduces tear evaporation, as well as enables avoiding pathological changes in conjunctival and corneal epithelial cells.

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