DIAGNOSTIC TECHNIQUE AND METHOD OF THERAPY OF DRUG-INDUCED DRY EYE SYNDROME Russian patent published in 2015 - IPC A61F9/00 G01N33/53 A61N7/00 A61K31/573 A61K31/728 A61K36/835 A61K47/10 A61P27/02 

Abstract RU 2554818 C1

FIELD: medicine.

SUBSTANCE: invention aims at treating drug-induced dry eye syndrome (DI-DES). Treating DI-DES implies taking the past medical history, measuring tear production and eye xerosis values reduced and increased respectively in relation to the norm. Unpreserved ocular hypotensive medications are prescribed in the patient. Unpreserved artificial tears are also applied. The lachrymal fluid is analysed by a multicytokine technique. If the analysis shows increased concentrations of proinflammatory cytokines - interleukin-6, interleukin-8, interleukin-12, Th-1 - interleukin-2, interferon-gamma, and Th-2 - interleukin-4, by min 30% in relation to the patient's age norm, a chronic immune ocular inflammation is detected. That requires transpalpebral Blepharogel-1 phonophoresis and 1% hydrocortisone ointment phonophoresis on the sub-mastoidal region from both sides; the therapeutic course is 8-10 daily procedures.

EFFECT: optimal conditions for diagnosing and reasoned differentiated therapy of DI-DES that enables prescribing the pathogenetically reasoned therapy in due time and increasing the efficacy of the therapeutic exposure.

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Authors

Janchenko Sergej Vladimirovich

Sakhnov Sergej Nikolaevich

Varlashina Evgenija Valentinovna

Malyshev Aleksej Vladislavovich

Kirichenko Ljudmila Ironovna

Dates

2015-06-27Published

2014-02-04Filed