FIELD: medicine, pharmaceutics.
SUBSTANCE: dosage form for local application in the form of cream or ointment contains as effective amount of voriconazole or its pharmaceutically acceptable salt, or a pharmaceutical carrier. Said dosage form of voriconazole contains max. 3 wt % of water. What is also described is a method for preparing the dosage form of voriconazole for treating local and non-systemic mycotic infections in an individual.
EFFECT: dosage form for local application under the invention maintains storage stability at temperature approximately 40°C and relative humidity approximately 75% for at least three months and has total storage impurity content is no more than 9 wt % as related to total weight of the dosage form.
12 cl, 1 dwg, 30 ex
