FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to pharmaceutical and medicine, and concerns a topical pharmaceutical formulation, including in the form of gel containing effective amounts of (a) polymer microspheres containing adapalene of average size 1-100 mcm, and (b) clindamycin, as well as a method of treating acne with the above formulations are storage-stable at temperature approximately 40°C and relative air humidity approximately 75% for at least 3 months.
EFFECT: developing the method of treating acne.
17 cl, 9 tbl, 7 ex
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