Show metadata Hide metadata

(19)

(11)

2 477 283

(13)

(51)

IPC

C07D493/08(2006-01-01)

A61K31/335(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2012107053/04, 2012-02-27

(24)

Start date

2012-02-27

(22)

Actual filing date

2012-02-27

(45)

Published

2013-03-10

(72)

Inventor

Tolstikova Tat'Jana GenrikhovnaPavlova Alla ViktorovnaMorozova Ekaterina AleksandrovnaMikhal'Chenko Oksana StanislavovnaIl'Ina Irina ViktorovnaKorchagina Dina VladimirovnaVolcho Konstantin PetrovichSalakhutdinov Nariman Faridovich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauki Novosibirskij Institut Organicheskoj Khimii Im. N.N. Vorozhtsova Sibirskogo Otdelenija Rossijskoj Akademii Nauk So Ran)

4,7-DIMETHYL-2-(2,4,5-TRIMETHOXYPHENYL)-3,4,4a,5,8,8a-HEXAHYDRO-2H-4,8-EPOXYCHROMEN POSSESSING ANALGESIC ACTIVITY Russian patent published in 2013 - IPC C07D493/08 A61K31/335 A61P29/00

Abstract RU 2477283 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutics, more specifically to new 4,7-dimethyl-2-(2,4_,5-trimethoxyphenyl)-3,4,4a,5,8,8a-hexahydro-2H-4,8-epoxychromen of formula possessing high analgesic activity, and may be used in medicine.

EFFECT: compound possess low toxicity and is synthetised from the available natural compound α-pinene.

1 cl, 4 ex, 2 tbl

Similar patents RU2477283C1

Title	Year	Author	Number
2-(4-HYDROXY-3-METHOXYPHENYL)-4,7-DIMETHYL-3,4,4a,5,8,8a-HEXAHYDRO-2H-CHROMEN-4,8-DIOL - NOVEL ANALGESIC AGENT	2010	Tolstikova Tat'Jana Genrikhovna Pavlova Alla Viktorovna Morozova Ekaterina Aleksandrovna Il'Ina Irina Viktorovna Ardashov Oleg Vasil'Evich Korchagina Dina Vladimirovna Volcho Konstantin Petrovich Salakhutdinov Nariman Faridovich	RU2430100C1
APPLICATION OF 4,7-DIMETHYL-2-(PROP-1-ENYL)-3,4,4a,5,8,8a-HEAHYDRO-2H-CHROMEN-4,8-DIOL AS ANALGESIC	2009	Tolstikova Tat'Jana Genrikhovna Pavlova Alla Viktorovna Morozova Ekaterina Aleksandrovna Il'Ina Irina Viktorovna Volcho Konstantin Petrovich Salakhutdinov Nariman Faridovich	RU2418578C1
2-(3-HYDROXY-4-METHOXYPHENYL)-4,7-DIMETHYL-3,4,4a,5,8,8a-HEXAHYDRO-2H-CHROMEN-4,8-DIOL AS ANALGESIC AGENT	2013	Tolstikova Tat'Jana Genrikhovna Pavlova Alla Viktorovna Morozova Ekaterina Aleksandrovna Mikhal'Chenko Oksana Stanislavovna Il'Ina Irina Viktorovna Pokushalov Evgenij Anatol'Evich Volcho Konstantin Petrovich Salakhutdinov Nariman Faridovich	RU2506079C1
4,7-DIMETHYL-3,4,4A,5,8,8A-HEXAHYDROSPIRO[CHROMENE-2,1'-CYCLOHEXANE]-4,8-DIOL AS AN ANALGESIC AGENT	2019	Ilina Irina Viktorovna Pavlova Alla Viktorovna Morozova Ekaterina Aleksandrovna Tolstikova Tatyana Genrikhovna Volcho Konstantin Petrovich Salakhutdinov Nariman Faridovich	RU2713946C1
2H-CHROMEN DERIVATIVES AS ANALGESIC MEANS	2014	Khaid Ekaterina Vladimirovna Pavlova Alla Viktorovna Mikhal'Chenko Oksana Stanislavovna Korchagina Dina Vladimirovna Tolstikova Tat'Jana Genrikhovna Volcho Konstantin Petrovich Khazanov Veniamin Abramovich Salakhutdinov Nariman Faridovich	RU2555361C1
DERIVATIES OF 4,4,7-TRIMETHYL-2-PHENYL-4a,5,8,8a-TETRAHYDRO-4H-BENZ[1,3]DIOXINE-8-OL - AS ANALGESIC AGENTS	2009	Tolstikova Tat'Jana Genrikhovna Pavlova Alla Viktorovna Morozova Ekaterina Aleksandrovna Il'Ina Irina Viktorovna Volcho Konstantin Petrovich Salakhutdinov Nariman Faridovich	RU2409353C1
8-(TRIFLUOROMETHYL)BENZO[f][1,2,3,4,5]PENTATHIEPIN-6-AMINE AS ANALGESIC	2011	Tolstikova Tat'Jana Genrikhovna Pavlova Alla Viktorovna Morozova Ekaterina Aleksandrovna Khomenko Tat'Jana Mikhajlovna Volcho Konstantin Petrovich Salakhutdinov Nariman Faridovich	RU2453311C1
3-ARYL-4A-ISOPROPYL-4AN-CHROMENO[6',7':4,5]FURO[3,2-C][1,2]OXAZINE-8-ONES WITH ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY	2016	Shults Elvira Eduardovna Lipeeva Alla Viktorovna Dolgikh Margarita Petrovna Tolstikova Tatyana Genrikhovna	RU2622768C1
5,7-DIMETHYL-1,3-DIAZAADAMANTAN-6-ONE DERIVATIVES CONTAINING MONOTERPENE RESIDUE, NOVEL ANALGESIC AGENTS	2014	Ponomarev Konstantin Jur'Evich Pavlova Alla Viktorovna Suslov Evgenij Vladimirovich Korchagina Dina Vladimirovna Tolstikova Tat'Jana Genrikhovna Volcho Konstantin Petrovich Salakhutdinov Nariman Faridovich	RU2564446C1
PHARMACEUTICAL COMPOSITIONS OF THIOCHROMENOL BASED ON A HEXAHYDRO-HETEROCYCLIC COMPOUND WITH ANALGESIC EFFECT, AND METHODS FOR THEIR USE IN DOMESTIC AND FARM ANIMALS	2022	Davydenkov Valerij Nikolaevich	RU2812294C2

RU 2 477 283 C1

Authors

Tolstikova Tat'Jana Genrikhovna

Pavlova Alla Viktorovna

Morozova Ekaterina Aleksandrovna

Mikhal'Chenko Oksana Stanislavovna

Il'Ina Irina Viktorovna

Korchagina Dina Vladimirovna

Volcho Konstantin Petrovich

Salakhutdinov Nariman Faridovich

Dates

2013-03-10—Published

2012-02-27—Filed