FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, namely physiology, pathophysiology and pharmacology, and may be used for an anxiolytic (antianxiety) effect. Substance of the invention consists in the use of peptide Gly-His-Lys of formula (NH2)Gly-His-Lys(COOH) for the anxiolytic effect. The experimental use of peptide Gly-His-Lys in single doses of 0.5 and 5 mcg/kg of body weight 12 minutes before the beginning of the examination causes the manifested anxiolytic effect.
EFFECT: invention provides the use of peptide Gly-His-Lys by the new application, namely for anxiolytic action.
1 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
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