METHOD FOR PREPARING PHARMACEUTICAL MICROCAPSULES OF CEPHALOSPORINS Russian patent published in 2013 - IPC A61K31/545 A61K9/58 A61K47/36 A61J3/07 B01J13/02 

Abstract RU 2482849 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical microcapsulation of cephalosporins related to β-lactam antibiotics. As a microcapsule shell, the method of pharmaceutical microcapsulation of cephalosporins uses konjac gum; the microcapsules are prepared by physical-chemical technology implying the precipitation in a non-solvent using two precipitants - carbinol and diethyl ester in ratio 1:3; the method is conducted at 25°C with no special equipment.

EFFECT: invention provides simplified and accelerated preparation of the water-soluble pharmaceutical microcapsules of cephalosporins in konjac gum, loss reduction in preparing the microcapsules (higher yield-mass).

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RU 2 482 849 C1

Authors

Bykovskaja Ekaterina Evgen'Evna

Krolevets Aleksandr Aleksandrovich

Dates

2013-05-27Published

2012-04-09Filed