METHOD FOR INCREASING EFFECTIVENESS OF HEMODIAFILTRATION IN ACUTE HEPATIC FAILURE IN CARDIOSURGICAL PATIENTS Russian patent published in 2013 - IPC A61M1/14 A61K31/715 A61P43/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to efferent medicine and may be used in hemodiafiltration in acute hepatic failure in the cardiosurgical patients. For this purpose, the bilirubin values more than 80 mcmole/l and the urea values more than 15 mmol/l requires introducing a solution as a dialysate to increase the clearance of toxic metabolites associated with plasma proteins. This solution is a standard bicarbonate solution of the dialysate added by 10% poly-(O₂-hydroxyethyl)-starch in ratio 1:1. That is followed by the prolonged venovenous hemodiafiltration at the length of 5-10 h.

EFFECT: method enables providing the high clinical effectiveness in the given pathology in the cardiosurgical patients by creating both a diffusion gradient, and an oncotic gradient ensuring a consistency of the oncotic pressure of the dialysate.

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