METHOD FOR PHOTOELECTROCOLORIMETRIC DETERMINATION OF SULPHANILAMIDE PREPARATIONS Russian patent published in 2013 - IPC G01N33/15 G01N31/22 

FIELD: chemistry.

SUBSTANCE: invention can be used for photoelectrocolorimetric determination of sulphanilamide preparations - streptocide, sulfadimezin, ethazol, sulfalene, phtalazol, sulfathiazole, sulfadimethoxine, sulfamonomethoxine in factory main laboratories, in analytical laboratories, in biochemical laboratories of clinics and in forensic chemical laboratories. The method involves dissolving a medicinal agent in 0.1M hydrochloric acid solution in case of sulfalene and phtalazol or 0.1M alkali solution in case of streptocide, sulfadimezin, ethazol, sulfathiazole, sulfadimethoxine or sulfamonomethoxine, holding on a hot water bath while stirring until complete dissolution, cooling and adding the same solution to the mark, further treatment of an aliquot part of the prepared solution with 0.1M potassium hydroxide solution (only in case of phtalazol and sulfalene) and 1% alkaline solution of sodium nitroprusside, 3% hydrogen peroxide solution and subsequent photoelectrocolorimetry of coloured solutions at wavelength of 670 nm.

EFFECT: high sensitivity, selectivity and accuracy of determining medicinal substances in pharmacopoeial preparations.

2 cl, 9 dwg, 2 ex