METHOD FOR SIMULATING CHRONIC CYTOSTATIC MYELOSUPPRESSION Russian patent published in 2013 - IPC G09B23/28 

Abstract RU 2488890 C1

FIELD: medicine.

SUBSTANCE: for the purpose of trial of a therapeutic preparation to correct hematological disorders, myelosuppression in simulated in mice by intraperitoneal introduction of cyclophosphane 200 mg/kg once per 7 days for 5 weeks to achieve stable meylosuppression shown by the neutrophil count and the committed granulomonocytopoiesis progenitor count.

EFFECT: method enables studying the possibilities of hematopoietic regeneration and pharmacological correction of the blood system disorders by the multiple cytostatic effect.

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RU 2 488 890 C1

Authors

Dygaj Aleksandr Mikhajlovich

Skurikhin Evgenij Germanovich

Pershina Ol'Ga Viktorovna

Khmelevskaja Ekaterina Sergeevna

Ermakova Natalija Nikolaevna

Dates

2013-07-27Published

2012-02-24Filed