METHOD FOR PREVENTION OF CATTLE BRUCELLOSIS Russian patent published in 2013 - IPC A61K39/10 A61P31/04 

FIELD: medicine.

SUBSTANCE: invention refers to veterinary science, particularly biotechnology. The method for prevention of cattle is as follows: A protective Brucella antigen complex in a dose of 5 to 10 mg dissolved in 5 ml 0.9% sodium chloride is administered to the animals. The animals are re-immunised 10 months later with detecting the latent infection on the 15^th and 180^th days, and finding the adult non-responsive and immune deficient animals by the agglutination reaction on the 15^th day with a 5 IU titer. The immunisation is combined with animal's blood sampling and brucellosis analysis. Using the Brucella antigen complex in a dose of 5-10 mg in the presented method for prevention of cattle brucellosis contributes to the protection against brucellosis using commercial vaccines, identifies the latently infected animals, provides an ability to test a specific immune status, increases the efficacy of diagnostic and veterinary-sanitary measures and eliminates the potential risk for live vaccines.

EFFECT: combined immunisation and blood sampling for brucellosis analysis can reduce the period of the non-immune state of the body, reduces the effects of stress factors on food-producing animals and increases the cost-effectiveness of specific interventions.

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