ANTACID AND LAXATIVE TABLET Russian patent published in 2013 - IPC A61K33/08 A61K47/12 A61K47/32 A61K47/38 A61K9/20 A61P1/04 A61P1/10 A61J3/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to an antacid and laxative tablet that contains magnesium oxide particles of the diameter of 0.5 to10 mcm as a main ingredient in the amount of 85 to 96 wt %. The claimed tablet contains crystalline cellulose 2-8 wt % as a binding agent, sodium croscarmellose 0.8-2.5 wt % as a disintegrating agent 1, insoluble polyvinyl pyrrolidone 1-3.5 wt % as a disintegrating agent II and a lubricant 0.5-2 wt %. The invention also refers to a method for preparing the above tablet that involves the mixing of the magnesium oxide particles, crystalline cellulose and the lubricant, and the dry granulation of the prepared mixture to produce the magnesium oxide granules, the mixing of crystalline cellulose, insoluble polyvinyl pyrrolidone and the lubricant with the magnesium oxide granules, and the tableting of the produced granules. The invention also refers to using the claimed tablet for antacid and laxative applications.

EFFECT: invention provides preparing the tablet that preserves the long-storage properties of fast disintegration, possess high friability and forms fewer impact cracks and splits.

15 cl, 15 tbl, 1 dwg, 30 ex