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(19)

(11)

2 504 382

(13)

(51)

IPC

A61K31/573(2006-01-01)

A61K31/58(2006-01-01)

A61K9/14(2006-01-01)

A61K9/72(2006-01-01)

A61K47/26(2006-01-01)

A61P11/00(2006-01-01)

A61P11/06(2006-01-01)

(21) (22)

Application

2012124231/15, 2012-06-13

(24)

Start date

2012-06-13

(22)

Actual filing date

2012-06-13

(45)

Published

2014-01-20

(72)

Inventor

Malin Aleksandr AleksandrovichMikhajlov Oleg RostislavovichUvarov Nikolaj Aleksandrovich

(73)

Holder

Sholeks Development Gmbkh

INHALATION PREPARATION FOR TREATING BRONCHAIL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND METHOD FOR PREPARING IT Russian patent published in 2014 - IPC A61K31/573 A61K31/58 A61K9/14 A61K9/72 A61K47/26 A61P11/00 A61P11/06

Abstract RU 2504382 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to medicine and pharmaceutical industry and describes an inhalation preparation for treating bronchial asthma and chronic obstructive pulmonary disease, containing micronized budesonide and micronised formoterol fumarate dehydrate as active ingredients, wherein the preparation contains a carrier presented by lactose of average particle diameter 1 to 10 mcm and sodium benzoate of bulk density 0.30-0.50 g/cm³, in the following proportions of the ingredients per a dose of the preparation: budesonide 50 mcg - 800 mcg, formoterol fumarate dehydrate 4.5 mcg - 18 mcg, lactose 5 mg - 50 mg, sodium benzoate 0.01 mg - 5 mg. What is also described is a method for producing the given preparation.

EFFECT: invention provides a higher percentage of a fraction of the active substances and respectively higher effectiveness.

4 cl, 8 ex

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RU 2 504 382 C1

Authors

Malin Aleksandr Aleksandrovich

Mikhajlov Oleg Rostislavovich

Uvarov Nikolaj Aleksandrovich

Dates

2014-01-20—Published

2012-06-13—Filed