PHARMACEUTICAL INHALED MEDICATION FOR TREATMENT OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE LUNG DISEASE, CONTAINING MICRONISED TIOTROPIUM BROMIDE AS ACTIVE SUBSTANCE AND METHOD OF ITS PRODUCTION Russian patent published in 2014 - IPC A61K9/72 A61K31/46 A61K47/06 A61K47/26 A61P11/06 

Abstract RU 2522213 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine and the pharmaceutical industry and describes a pharmaceutical inhaled medication for treatment of bronchial asthma and chronic obstructive lung disease, containing micronised tiotropium bromide as an active substance, and which contains as a carrier lactose with the average particle size of 120-200 mcm, sodium benzoate, sieved with a bulk density within the range of 0.30-0.50 g/cm3 and sodium benzoate micronised with the average particle size of 0.5-10 mcm with a specified content of components per a dose of medication.

EFFECT: invention provides higher percent of a respirable fraction of the active substance and, therefore, higher pharmacological activity.

3 cl, 10 ex

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RU 2 522 213 C2

Authors

Malin Aleksandr Aleksandrovich

Mikhajlov Oleg Rostislavovich

Uvarov Nikolaj Aleksandrovich

Dates

2014-07-10Published

2012-06-07Filed