PHARMACEUTICAL COMPOSITION CONTAINING ENZYME RIBONUCLEASE AND GLYCYRRHIZIC ACID OR SALTS THEREOF: AMMONIUM OR DIPOTASSIUM OR TRISODIUM GLYCYRRHIZINATE Russian patent published in 2014 - IPC A61K38/43 A61K38/44 A61K31/155 A61K31/7012 A61P17/02 A61P31/00 

Abstract RU 2504396 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry and represents a composition for treating wounds, ulcers, erosions, burns, freeze burns adhesions, as well as infections caused by the gram-positive and gram-negative bacteria Staphylococcus spp., Streptococcus spp., Enterococcus spp., Shigella spp., Escherichia spp., Salmonella spp., Proteus spp., Acinetobacter spp., Citrobacter spp., Pseudomonas spp., Serratia spp., Klebsiella spp., Antracoides spp., Cryptococcus spp., pathogenic fungi of the genera Microsporum, Trichophyton, Nocardia, Aspergillus, yeast-like fungi of the genus Candida (including the multiresistant strains), as well as Actinomycetes and some pathogenic protozoa (Entamoeba histolytica, Trichomonas vaginalis), containing an active ingredient in the form of 0.001-5.0 wt % of collagenase, 0.001-5.0 wt % of lysozyme and/or 0.001-5.0 wt % of sangvitirine, and an carrier in the form of 0.05-1.0 wt % of p-cyclodextrine or liposomes, and acceptable excipients.

EFFECT: invention provides stability and maintained enzymic activity for a long period of time, deep penetration into an affected skin area, potentiated complex antimicrobial and anti-adhesion action.

2 cl, 10 ex, 4 tbl

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RU 2 504 396 C1

Authors

Klopotenko Leonid Leonidovich

Dates

2014-01-20Published

2012-09-10Filed