PHARMACEUTICAL COMPOSITION CONTAINING ENZYME RIBONUCLEASE AND GLYCYRRHIZIC ACID OR SALTS THEREOF: AMMONIUM OR DIPOTASSIUM OR TRISODIUM GLYCYRRHIZINATE Russian patent published in 2014 - IPC A61K38/46 A61K31/704 A61P31/14 

Abstract RU 2504397 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to pharmaceutical industry and represents a composition for treating and preventing viral infections caused by RNA-containing viruses, such as influenza, parainfluenza, parotitis, rubeola viruses, respiratory syncytial virus, rubella virus, rhinovirus, containing an active ingredient in the form of 0.001-0.5 wt % of ribonuclease (RNA-ase) and 0.001-0.5 wt % of glycyrrhizinic acid or a salt thereof: ammonium or dipotassium or trisodium glycyrrhizinate; the carriers are as follows: 0.05-1.0 wt % of a polymer carrier, 0.001-5.0 wt % of β-cyclodextrins or hydrogenised lecitin and acceptable excipients.

EFFECT: invention provides the preserved activity of the enzyme ribonuclease for a longer period of time, the higher stability and potentiated combined antiviral action.

1 cl, 9 ex, 3 tbl

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RU 2 504 397 C1

Authors

Klopotenko Leonid Leonidovich

Dates

2014-01-20Published

2012-10-25Filed