FIELD: chemistry.
SUBSTANCE: present invention relates to novel alkyl [(S)-1-((S)-2-{5-[4-(4-{2-[(S)-1-((S)-2-methoxycarbonylamino-3-methyl-butyryl)-pyrrolidin-2-yl]-3H-imidazol-4-yl}-buta-1,3-diinyl)-phenyl]-1H-imidazol-2-yl}pyrrolidine-1-carbonyl)-2-methyl-propyl]-carbamate naphthalene-1,5-disulphonates of general formula 1, which are NS5A inhibitors and can be used as an active component for producing a pharmaceutical composition and an antiviral medicinal agent for treating and preventing viral diseases caused by hepatitis C virus (HCV) and hepatitis GBV-C virus. In general formula 1 R denotes C1-C3alkyl.
EFFECT: obtaining novel compounds.
6 cl, 2 tbl, 6 ex
Title |
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Author |
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ALKYL [2-(2-{5-[4-(4-{2-[1-(2-METHOXYCARBONYLAMINO-ACETYL)-PYRROLIDIN-2-YL]-3H-IMIDAZOL-4-YL}-PHENYL)-BUTA-1,3-DIINYL]-1H-IMIDAZOL-2-YL}-PYRROLIDIN-1-YL)-2-OXO-ETHYL]-CARBAMATE, PHARMACEUTICAL COMPOSITION, MEDICATION, METHOD OF TREATING VIRAL DISEASES |
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