POLYSACCHARIDE FROM Bifidobacterium infantis STRAIN AND USE THEREOF TO TREAT OR PREVENT INFLAMMATORY DISORDERS Russian patent published in 2014 - IPC C08B37/00 A61K31/715 A61K35/74 A61P1/04 A61P37/02 

Abstract RU 2511044 C2

FIELD: chemistry.

SUBSTANCE: group of inventions relates to biotechnology and medicine. Disclosed is a polysaccharide which is isolated from the Bifidobacterium infantis NCIMB 41003 strain and has the structure [-β(1,3)-D-GalpNAc-β(1,4)-D-Glcp-]n, where said disaccharide unit repeats n times, which yields a polysaccharide with molecular weight greater than 100000 Da. The polysaccharide exhibits immunomodulating activity and is used in preparing medicinal agents for treating or preventing undesirable inflammatory activity, undesirable gastrointestinal inflammatory activity, rheumatoid arthritis and autoimmune disorders.

EFFECT: pharmaceutical composition for treating and preventing inflammatory disorders and a food product containing the isolated polysaccharide are disclosed.

9 cl, 6 dwg, 3 ex

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RU 2 511 044 C2

Authors

Grant Rejmond Alan

O'Makhouni Lajam

Shejl Barbara

Dates

2014-04-10Published

2008-05-02Filed