TOPICAL COMPOSITION POSSESSING ANTI-INFLAMMATORY, ANALGESIC, ANTIRHEUMATIC AND ANTIBACTERIAL ACTIVITY AND METHOD FOR PREPARING IT Russian patent published in 2014 - IPC A61K31/19 A61K31/385 A61P29/00 A61P31/04 

Abstract RU 2519330 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine and concerns a local topical composition characterised by the fact that it contains synthetic lipoic acid; 95% ethyl alcohol; 1,2-propylene glycol, polyacrylic acid (any other hydrophilic gelling agent), triethanolamine, purified water; a method for preparing the local topical composition characterised by the fact that synthetic lipoic acid is dissolved while stirring in mixed ethyl alcohol and propylene glycol; at the same time polyacrylic acid is dispersed in a specified amount of water sufficient to reduce the ratio of the ingredients up to 100 wt %, after 3-hour swelling, the prepared solution is added to synthetic lipoic acid dissolved in mixed ethyl alcohol and propylene glycol and mixed up; the prepared composition is neutralised by a triethanolamine solution to pH 5.5-6.5 and mixed to form a light-yellow transparent gel-like mass.

EFFECT: group of inventions provides high antirheumatic, anti-inflammatory and analgesic activity, as well as effective antibacterial and anti-burn action.

4 cl, 4 ex, 1 tbl, 3 dwg

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Authors

Khannanov Timur Shamilovich

Anisimov Aleksandr Nikolaevich

Zaljaljutdinova Luiza Nail'Evna

Zvereva Elena Jur'Evna

Nasybullina Nailja Marsovna

Garaev Ramil Sufiakhmetovich

Zverev Renat Rustehmovich

Valiev Ravil' Shamilovich

Sabirova Al'Fija Jakh"Jaevna

Dates

2014-06-10Published

2011-10-31Filed