CELL-PENETRATING PEPTIDES AND POLYPEPTIDES FOR MICROORGANISM CELLS Russian patent published in 2014 - IPC C07K7/08 C07K7/06 C07K14/00 C07K19/00 C12N15/11 C12N15/63 C12N1/00 C12N1/21 C12R1/19 

FIELD: medicine.

SUBSTANCE: invention refers to genetic engineering and can be used for methane-producing cell permeability control. What is prepared is a polypeptide able to permeate into a methane-producing cell and to increase its permeability, characterised by an amino acid sequence SEQ ID NO:117, 118 or 119 or being at least 90% identical to the above sequence, or at least 15 sequential amino acids of the above sequence. What is also prepared is a polynucleotide coding the above polypeptide cloning and expressing vectors used for producing host cells producing the polypeptide or used for the vector replication. The polypeptide can contain a fluorescent tag on an N-terminal amino acid residue.

EFFECT: invention enables providing higher methane-producing cell permeability.

18 cl, 35 dwg, 3 ex