FIELD: biotechnology.
SUBSTANCE: invention relates to new overlapping peptide (OLP) immunogens, and can be used in medicine to prevent or treat HIV infection. An immunogenic fusion protein consisting of polypeptide segments with SEQ ID NOs:1-16, linked by amino acid linkers, is obtained. This invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens, as well as vaccines comprising the said immunogens.
EFFECT: provided induction of HIV-specific T-cell immune responses in the host.
51 cl, 8 dwg, 5 tbl, 4 ex
| Title |
Year |
Author |
Number |
| IMMUNOGENS FOR VACCINATION AGAINST HIV |
2013 |
- Brander, Christian
- Mothe Pujadas, Beatriz
- Llano, Anuska
|
RU2721274C2 |
| VIRUS-LIKE PARTICLES WITH HIGH-DENSITY COATING FOR INDUCTION OF ANTIBODY EXPRESSION |
2017 |
- Carrillo Molina, Jorge
- Molinos-Albert, Luis, M.
- Blanco Arbues, Julian, M.
|
RU2813282C2 |
| RAPID SELECTION METHOD FOR HIV GP-120 VARIANTS |
2012 |
- Juste Errans Marija Eloiza
- Sanches Merino Viktor
- Ferrejra Karolina
|
RU2603732C2 |
| MUTANT POLYMERASES OF HEPATITIS B VIRUS |
2012 |
- Marten Perrin
- Silvestr Natali
- Marshan Zhan-Baptist
|
RU2625021C2 |
| RECOMBINANT VACCINE OF FELINE LEUKEMIA VIRUS CONTAINING OPTIMISED GENE OF FELINE LEUKEMIA VIRAL ENVELOPE |
2012 |
|
RU2591817C2 |
| VIRUS OF CAPRINE ARTHRITIS-ENCEPHALITIS PROVIDING IMMUNE PROTECTION AGAINST HIV- 1 INFECTION |
1997 |
- Duvas Andzhelin
- Ehresmann Glenn
|
RU2194529C2 |
| ISOLATED NUCLEIC ACID ENCODING FELINE LIGAND CD86, DIAGNOSTIC OLIGONUCLEOTIDE, CLONING VECTOR, VACCINE, METHODS FOR INDUCTION OR SUPPRESSION OF IMMUNITY IN CAT |
1999 |
- Kollison Ehllen V.
- Choj In-Soo
- Uinslou Barbara Dzh.
- Kochran Mark D.
|
RU2263145C2 |
| METHODS AND COMPOSITION FOR INHIBITION OF HIV-1 MULTIPLICATION |
2001 |
|
RU2275379C2 |
| INFLUENZA HAEMAGGLUTININ AND NEURAMINIDASE VARIANTS |
2010 |
- Dzin Khong
- Chehn Sin
- Subbarao Kanta
|
RU2535970C2 |
| SIMIAN ADENOVIRUS NUCLEIC ACID- AND AMINO ACID-SEQUENCES, VECTORS CONTAINING SAME, AND USE THEREOF |
2010 |
- Kolloka Stefano
- Nikosija Alfredo
- Korteze Rikkardo
- Ammendola Virdzhinija
- Ambrozio Marija
|
RU2604815C2 |
