METHOD FOR PREDICTION OF CHRONICITY OF VIRAL HEPATITIS B IN CHILDREN WITH FOOD ALLERGY Russian patent published in 2014 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: presented invention refers to medicine, namely to the investigation of physical and chemical properties of biological fluids, and can be used for the prediction of chronicity of viral hepatitis B in children suffering from acute food allergy. The method for the prediction of the chronicity of viral hepatitis B in the children with food allergy involving clinical and laboratory examinations, including a biochemical blood assay for bilirubin, enzymes, and an enzyme immunoassay for hepatitis B markers at admission to hospital. The substance of the method: radioimmunoassay is used to determine blood serum HBs-antigenemia, gastrin, tripsin, total IgE, and cortisol, and if the derived HBs-antigenemia level is more than 15,000 r.im./ml, while the gastrin value is more than 50.0 ng/ml; the trypsin level is more than 450.0ng/ml; the total IgE value is more than 400.0 IU/ml, and the cortisol level is below 400.0 ng/ml, the chronicity of the disease is predicted.

EFFECT: firstly, the invention provides predicting the chronicity of hepatitis B at the early stages of the disease that provides advising effective therapeutic measures and increasing a rate of convalescence in the presented category of children; secondly, it enables diagnosing the functional activity of the upper digestive system and holding the well-timed measures to prevent its pathology from progressing.

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