FIELD: medicine.
SUBSTANCE: invention refers to medical and molecular genetics. There are described genetic constructs expressing RNA sequences and genes coding proteins possessing the antiviral activity on human immunodeficiency virus. The genetic constructs contain a sequence coding the human TRIM5a modified protein. The invention can be used in scientific investigations.
EFFECT: presented constructs enable providing the higher expression of the modified gene of the human TRIM5a.
40 cl, 4 dwg, 3 tbl, 13 ex
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