FIELD: medicine, pharmacology.
SUBSTANCE: group of the inventions relates to the field of pharmaceutics and medicine and concerns a liquid composition containing the agonist GLP-1 and/or its pharmacologically acceptable salt, insulin glargin and/or its pharmacologically acceptable salt and, optionally, at least one pharmacologically acceptable auxiliary substance characterized by that the given composition contains methionine and has pH value from 3.5 up to 5. Also the combination of compositions, set containing a combination, and the use for obtaining of medicinal preparation for treatment of pancreatic diabetes are offered.
EFFECT: group of inventions ensures the storage stability and chemical integrity of active components.
27 cl, 2 ex, 4 dwg
Title | Year | Author | Number |
---|---|---|---|
COMBINATION OF INSULIN AND GLP-1 AGONIST | 2009 |
|
RU2532378C2 |
COMBINATION OF INSULIN AND GLP-1 AGONIST | 2014 |
|
RU2682671C2 |
PHARMACEUTICAL COMPOSITION CONTAINING GLP-1 AGONIST AND METHIONINE | 2010 |
|
RU2573995C2 |
INSULIN PREPARATION CONTAINING METHIONINE | 2010 |
|
RU2540485C2 |
NOVEL INSULIN DERIVATIVES WITH STRONGLY SLOWED PROFILE TIME/ACTION | 2009 |
|
RU2529952C2 |
STABILISED COMPOUNDS OF EXENDIN-4 | 2003 |
|
RU2376314C2 |
COMPOSITIONS OF LONG-ACTING INSULIN | 2011 |
|
RU2564104C2 |
COMPOSITIONS OF LONG-TERM ACTION INSULINS | 2015 |
|
RU2642662C2 |
NOVEL INSULIN DERIVATIVES WITH EXTREMELY DELAYED TIME/ACTION PROFILE | 2009 |
|
RU2524423C2 |
PRODRUGS CONTAINING EXENDIN CONJUGATE-LINKER | 2011 |
|
RU2593774C2 |
Authors
Dates
2014-12-27—Published
2010-11-11—Filed